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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0be4d174e53eb05fd9a621e2b4afc44f9456ceea4bba9127aeaa77d30868ce' 
  AND token = '5k5kHJop7mOB25zr334fXEuQMfbPn8ftvOZda1CygZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00131

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}