SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d6ee6a0eec2effaa51e2eef010ec69da4da5e1eff48415b6afcdcd483efcaa' 
  AND token = 'PxlFhw+JPS9gDlWQuPR5Y1sv6FvTdSS/l+uZfXW3zCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}