SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1129497bd8b394976954c7addead3e2eefe832feb81fa4983f27df095e6a681' 
  AND token = 'UO5btkJFl7ERJO167a3EmSBiFact1BnZyC3tz+iOpwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}