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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260233f495b19ddee16f18cb1ba3f4186956b2f8edc2c5ab5091bc89a5c7d1a7' 
  AND token = 'KpQ2H4IfyLeXi7KVU9eCBW2ovidF1rNpg3MdlPH9vGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}