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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292a1f1fffda335720af6e16bc11d947ac21270b62f671bb27fb7c53c1cac2ab' 
  AND token = 'GGNrChsCDH/at2nGf4DlQhGeyqN8oEr4iG1Z2YjNTfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00161

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}