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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4142455fd5c1c7b19ed7a771a224e88367a781b50bc6f219fc5d3c10d143553c' 
  AND token = 'o9GvN4ayIGjJrGutRRK349w8k6OnAxmjQU3WUwkFHdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}