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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '566235fa7e288e596eada27a2bf5442025e1e0b6315e09d89b7703e0ca8af8d1' 
  AND token = '8RpKQ67eNP6W6KvOOdoSkB+ZKFPMSZZY63YZAWm70Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}