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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f8d93f1224e37fa01f958c633540d78e4801eec6a6fb646a9a78b6ed6dcf61' 
  AND token = 'ACZRvxil8TyOU+k66l0JWbgF1d6CO9fYHZ8m0DNQXxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}