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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae8ddc82764db7ea7a64e86dab02467f55ad195bd3c1b2c4c017a15176f26b28' 
  AND token = 's+pspB89bEbepVIKjAgaKNeQQbHr/tZURBYLysAOUHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}