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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124ce011f2fa7407845b277189787bcd0443958401a376bb29746be838b89e77' 
  AND token = 'Dkmsrj/l/9lbgxs7K1QcBQ6fWzC+rQTnS6na2fXijoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}