SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e3a13d7801ca59260728a3ed08e7139ae7f8e9363d7fd2e16af40b12ade795' 
  AND token = 'n7mWkZ2W5T1k/nPtwrLusON4O/a0aCRPdsiOi6/mNnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}