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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71257ce2095a30e54d1f66ad2d0c80ac5869425a1005e937ee12af4321766e2d' 
  AND token = '0Q1VEa+ybFWEGLgmISrSUXMnvy8Yv8WGEaRr0oTG2C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}