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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0f815efbcd00da5507a1210b60b25daab16691f09d4d707112ee6636d31044c' 
  AND token = 'NPQSmdpbySFF1S/GzIrQIrdw1d2iQbsTbPr+yDA8vDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}