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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fec6b2f9fd1832e81ab125084f23aaf30c9bda4db57e4ef295732e7153cb98' 
  AND token = '8+O3NbnQ8rel+r6INeVelILnptC0yyG4scaXhswt93M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}