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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '910006e64e1c3656219dc5014fd8e46fbbe22f228762db872e359d541cb54f73' 
  AND token = 'ThE840A0YX+025yrnIRZ81EN5HTum79bdDe9T6kjeok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}