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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15afe3bc6b7ee648797328bf01c465f8844a535f987351fa097a609b6edd40c' 
  AND token = 'RLe2cmULQ8W7i6ay0aQhCXdgDlGNNKiprNBgEETnP/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}