SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ebf9fd93e2a8e7e50e77b3cf6f9f113a7ebfad4fc9d3fcc39586a52fd915c91' 
  AND token = 'S2p5+2RTKhZ5M4dfNRA2HFkRz3ipnmJZS1jzbiRM+XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}