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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26546de7d5909b0a809d203a2381d0d1bba23d9ecf7b50a148c07d4e58c06611' 
  AND token = 'mX00l7ltG5Mt8zp8h3CCTW9H3kABdCKtJJFu+4E8fKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}