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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1b866639074ee7026a47bba7b88aca39fadbbbffdf09499819630a54a0d84e' 
  AND token = 'zMz1vS+8kbKmEDl6a1MdmDHBQjlLFwccz2yh12/2eao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}