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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '483915041410edb14cc8f3d9f2e2e58c3af8017363de802bcbc81eaa3ac919ac' 
  AND token = 'unisQ1Esaiz6WX4ejGDmappxHAxyZ6yY0ZKvo8ERZfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}