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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '670d43633ae2337f0a06d05d1d78cc3dee2a2444cf3902675514c748db1f0bdb' 
  AND token = 'OL6Gw9OtYgIsWwWwcT9RSjGLyx6uP/vq8t8QoyhWgek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}