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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e1c03b5218bc1f048d7cd0f17b7c54e0dc1e3daeb5ea459eb8d732f90c44922' 
  AND token = 'MKnFSRK6pB5TpnzmHMIsDHB8zsB511iByLP0mxPUCPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}