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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bdf6afba488c816d639d5cc68859b97c94d5dd7bb7b578c43cf4b0b795c2bb2' 
  AND token = 'hpn1O3nybArZqJx2xRxRWWS0Ft+wAR1QcWJH0kS/ayg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}