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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14821d9ef934af376ad8a776dc204800315e58260771938077176a43620251ba' 
  AND token = 'MY4lXeHbZL1eQ/O5n8dj2YlpK7WTHAASCIXBv2nGE5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}