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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d657201690d24d0cec4df38c144a67ea6414f82f429fb7a4b642b917d4b2ba' 
  AND token = 'KtZpgPBE2x++xiXc5BCIx0QfYoHO0s2NFBBtwK8dsww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}