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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c708d021ceccc8bbbc80b37c552dfb4b832a2aea30740e81689625ac00b36715' 
  AND token = 'hPoX9W+kRzXsEOq3LaIFtpTZVQETkXOPCFE8Iy2nCac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}