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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a850ef111079563d3f41a8ae07f645d3a42ec8c9fc2ca233f764b9ff82173ea' 
  AND token = 'YJ4wIpG+DhdQJ5STlyrIiMw+75cps3Y890DWNeU1XRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}