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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf5078e54b87433b58bdbd921a192177cb15d8667f2167d4bfa035ee223ce3b5' 
  AND token = 'PFR/pwml0awaLe5LZdZ50cmK4ot+fyzaT4iJpBozI7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}