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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2433c5fa7fa52d409f556088f5a973479f7e6b88c802b639ab2f2e05aee6a1c1' 
  AND token = 'KeJRPhlfdvCmzD3Y7c3fnq65v6ccZAELvwk5ZDTjjhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}