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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bdde4b1a90d5403382de531abfb060e5f11d0fe1a73f48e63d20adfb3eeb284' 
  AND token = 'HUUEYOgzaDbASpnJOrBL5RkG+uMR9dqdVQalbkMhV0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}