SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0e4e73e6c72be21ed64cb62ea40b700aafebc83d487102a9e39b77904f6af9' 
  AND token = 'U6f5XSr+sR3oJaAtYK5hAymU4LAsYMKLEXdMUjkHsJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}