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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ac02bb6827a29a728d17f88a96e5e4733297931ff68434024e8b2f76714a7a' 
  AND token = 'h39/eqASXiSSkL73fr8GkPt8AlPjKYX5jARH3BRe3lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}