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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e45dedadb80d540b39c849de9f04e77d268cf8647e34ee2ce74ed785eaa54c' 
  AND token = 'GLrtzl2w1KSA86G2fLHEP9XKD4bVK/NwvBkfT1PKZkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}