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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f5891e29d98621f0db4b377522c28354cece704ad45643468ad6cc8448a10a' 
  AND token = 'XWPM8zoJIPazzkHWOGa1PovaQ11R1ENy8XcC/mOT3Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}