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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79c760f945ad61f5f388539f7b641ca96f0dae7de36f60f844afda99cecb2250' 
  AND token = '1RCBnJ0OLYGDWqRrP0yJ0MuQC2Vn/xhAA/nzaI91B0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}