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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16956a0e2e0f17d03aec14ac77ff6c3adbd5084ae256d4cca08fc5accdd85551' 
  AND token = '2MD3CkrhD8u8zJqeCFT+vHUlUoUWL9YM4JWn64cRSZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}