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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63349af69277dbc8ebcb30be30bf768c3f672f5a27e0e2742517e86ad0d1f00' 
  AND token = 'FHBodroVxXkxYi8Hqq3x/5CNcdgr6aZBiSVDS8cqI9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}