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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a410ef610fcb8f5b5884d83f0a670b80993c3e22b1d34882fa05cdd00d8a94d8' 
  AND token = 'RIYNMY0P328GZvzLG41ZuN/WXOV3h3H4ip6sMhMVmWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}