SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e700a3b413bdb1bf09b577e7a222b079d11cdcd2d626d453c5bf2b9bc845c25d' 
  AND token = 'R8bCkIaROYYTiuUYTjEqGgka6xcpUAd5evjtGRDRu+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}