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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a943cc80353b318dd8742ac97af375b68af7819b2a9189bf494db6742187461' 
  AND token = '5nq04iLtc0kW9RcZjs80ZPqeD6AgYN3JYDtDIwrKnYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}