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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f57fc847372fb9c6a5d468d1469a0aaef4d082b730b0d0c6d357da92c49549d' 
  AND token = 'S37vT1wZOIj1TbEmlylcgS7uq9sl/AAP9GRtT8kmNVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}