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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641567ce87fb90f60f47cd9ff493fb4fc167fdba86856a30149fd40b2b86074c' 
  AND token = 'oB59BE9Yy4+VnzBhyeJHXyTsWD4c8Kbz7uQPZU0un08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}