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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0172831af7db2efb7eb868a42b53449a9133bb4c1aedc1a29e0cd4a65b6fac26' 
  AND token = 'MjMJZkmDkV1bfLi3nlzGQdO8z3WGlaPRlTwEtVdnkfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}