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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f71777774d01948feae01793c8be91d2f9764e43b994ee9eaf3b8db4cf897c80' 
  AND token = 'IBCrfUxsx/AZmy3JLJ+WtsJl3SEdCd8pcVBxMceVRtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}