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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2db9f42f4dd8a15199ed2208cbed5607c02f93c8a299e46c0e130162db204ec8' 
  AND token = 'eCfFEYUu4KSbtGTZ/cQQxHYAvrLrFGg9/WAUH2l19UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}