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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f2528209ff9eb3f331b960fca87a0203e14ed600205dfe699bc6a90f393e39' 
  AND token = '20zQ194OlvgurG4KUJrdmofCWDCPVS33iytt7pRrlJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}