SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45e63482f8e8763c28033b8f0807215919d9dbde2aee7fa77b6f115542d35ae' 
  AND token = 'J/e+OBpQYnmc8hLp18ihh/fRZJpSfae+ckdj6X0v2OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}