SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455cdfcb797e4b270d18fc59d9ea44aa85ca4f0a04b6d699179f0df42fa0841d' 
  AND token = 'c7iNDkSPkXM4zfDJ/0kvzPqjV9W7xdzgwJuJmgyvnv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}