SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8954bdd6c11460eaffcf6ccff60500c510a90fd0fbb9dec1174c6b45ab1c0a7' 
  AND token = '8OdW0M1hVUMuGKxLA2kyG4+lKqghy2YlgK5eXYMnLK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}