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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c7c87b0d83121ed413d1b48d80ff1ac1341d18b1ccdc661493e336738a75b29' 
  AND token = 'PEO80j4CJPuP4B+td9IvOhNdLobNQvWoamXHYvgugDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}